CELLS DEFICIENT IN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE
摘要
Compositions and methods for enhanced protein production provide cells deficient in hypoxanthine-guanine phosphoribosyltransferase. Methods for preparing the deficient cells, and methods for using the deficient cells to produce high levels of recombinant proteins are disclosed.
申请公布号
WO2013123408(A1)
申请公布日期
2013.08.22
申请号
WO2013US26454
申请日期
2013.02.15
申请人
SIGMA-ALDRICH CO. LLC;LIN, NAN;BORGSCHULTE, TRISSA;SEALOVER, NATALIE;GEORGE, HENRY;KAYSER, KEVIN
发明人
LIN, NAN;BORGSCHULTE, TRISSA;SEALOVER, NATALIE;GEORGE, HENRY;KAYSER, KEVIN