发明名称 |
IODINATED PRODUCTS INTENDED FOR A USE FOR THE MEDICAL IMAGING AND THEIR METHODS OF PREPARATION |
摘要 |
The present invention concerns an iodinated lipophilic compound of formula (I) or (II) : AG-R (I) or AG-X-R (II) wherein - AG represents an unsaturated or saturated (C8-C52) aliphatic hydrocarbon chain found in fatty acids having or not a double bond, an unsaturated or saturated aromatic cycle with an hydrocarbon chain, a sterol, an unsaturated or saturated (C8-C52) aliphatic hydrocarbon chain ended by an amino group having or not a double bound, - X represents a spacer such as a diacid, a diol (like aliphatic diol, polyethylene glycol comprising 1 to 50 ethylene glycol groups) or an amino acid, - R represents a benzene ring with one, two or three iodine atoms and a carboxylic group or an alcohol group. |
申请公布号 |
WO2013121284(A1) |
申请公布日期 |
2013.08.22 |
申请号 |
WO2013IB00429 |
申请日期 |
2013.02.14 |
申请人 |
UNIVERSITE DE STRASBOURG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
VANDAMME, THIERRY;LI, XIANG;ANTON, NICOLAS;ZUBER, GUY;ZHAO, MINJIN |
分类号 |
A61K49/04;C07C69/76;C07C69/84;C07D311/56;C07D311/72 |
主分类号 |
A61K49/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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