发明名称 |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR REDUCING ADIPOSE TISSUE INFLAMMATION |
摘要 |
The present invention relates to an inhibitor of interferon regulatory factor 5 (IRF5) activity or expression for use in a method for reducing adipose tissue inflammation in a subject. The present invention also relates to a method for screening a plurality of candidate compounds useful for reducing adipose tissue inflammation comprising the steps consisting of (a) testing each of the candidate compounds for its ability to inhibit interferon regulatory factor 5 activity or expression and (b) and positively selecting the candidate compounds capable of inhibiting said interferon regulatory factor 5 activity or expression. |
申请公布号 |
WO2013121034(A1) |
申请公布日期 |
2013.08.22 |
申请号 |
WO2013EP53148 |
申请日期 |
2013.02.18 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) |
发明人 |
VENTECLEF, NICOLAS;CLEMENT, KARINE;DALMAS, ELISE |
分类号 |
C12N15/113;A61K31/7088;A61P29/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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