发明名称 Heteroaryl compounds as PIKK inhibitors
摘要 The present invention provides compounds that are PIKK inhibitors, more specifically, mTOR and/or PI3Kαkinase inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of kinases, specifically PI3 kinases, more specifically, mTOR and/or PI3Kα, such as cancer. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
申请公布号 AU2010249040(B2) 申请公布日期 2013.08.22
申请号 AU20100249040 申请日期 2010.05.12
申请人 AMGEN INC. 发明人 BODE, CHRISTIANE;BOEZIO, ALESSANDRO;CHENG, ALAN C.;CHOQUETTE, DEBORAH;COATS, JAMES R.;COPELAND, KATRINA W.;HUANG, HONGBING;LA, DANIEL;LEWIS, RICHARD;LIAO, HONGYU;POTASHMAN, MICHELE;STELLWAGEN, JOHN;YI, SHUYAN;NORMAN, MARK;STEC, MARKIAN;PETERSON, EMILY A.;GRACEFFA, RUSSELL
分类号 C07D401/14;A61K31/437;A61K31/506;A61K31/52;A61K31/53;A61P35/00;C07D403/04;C07D403/14;C07D471/04;C07D487/04;C07D519/00 主分类号 C07D401/14
代理机构 代理人
主权项
地址