Pharmaceutical compositions resistant to abuse

摘要

A pharmaceutical composition and a shell for a pharmaceutical composition, the shell comprising an outer shell wall having an inner surface and extending from a first end to a second end, the outer shell wall having an opening at the first end and a maximum thickness of at least 1.0 mm, the shell having a length in the range from 4 mm to 20 mm. The pharmaceutical composition may comprise a matrix composition in a cavity of the shell. Further disclosed is a method for testing abuse-resistance of pharmaceutical compositions.