发明名称 (AZA)INDOLIZINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
摘要 (Aza)indolizine derivatives represented by Formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of serum uric acid level, prodrugs thereof, salts thereof or the like. In Formula (I), 0 to 2 of X1, X2, X3 and X4 are a nitrogen atom and the others are CR1; one of T1 and T2 represents cyano and the other represents a group represented by Formula (A), with the proviso that when T1 is cyano, at least one of X1 to X4 is a nitrogen atom; R1 independently represents a hydrogen atom, a halogen atom, a hydroxy group, C1-6 alkyl, C1-6 alkoxy or the like; ring U represents a benzene ring or the like; m represents integral number from 0 to 2; R2 independently represents a fluorine atom, a hydroxy group or the like.
申请公布号 US2013217878(A1) 申请公布日期 2013.08.22
申请号 US201113824147 申请日期 2011.09.28
申请人 IIZUKA MASATO;SHIMIZU KAZUO;KISSEI PHARMACEUTICAL CO., LTD. 发明人 IIZUKA MASATO;SHIMIZU KAZUO
分类号 C07D487/04;C07D471/04 主分类号 C07D487/04
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