发明名称 |
PROCESS FOR MAKING MULTIPARTICULATE GASTRORETENTIVE DOSAGE FORMS |
摘要 |
The instant invention relates to a process for making inherent low density particles, comprising the steps of (i) providing a powder mixture comprising a swelling agent; (ii) granulating the powder of step (i) with a granulating solution comprising a lipophilic agent into granules and (iii) drying the granules of step (ii). The instant invention further relates to multiparticulate oral gastro-retentive dosage forms comprising the inherent low density particles obtainable by the process.
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申请公布号 |
US2013217777(A1) |
申请公布日期 |
2013.08.22 |
申请号 |
US201113879990 |
申请日期 |
2011.10.20 |
申请人 |
KIRKORIAN JOEL SYLVAIN MICHEL;MELIATYS |
发明人 |
KIRKORIAN JOEL SYLVAIN MICHEL |
分类号 |
A61K9/16;A61K31/167 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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