METHOD FOR PRODUCING GLYCOPROTEIN HAVING MANNOSE RESIDUE AS NON-REDUCING END OF SUGAR CHAIN

摘要

Disclosed is a method for producing a glycoprotein using mammalian cells, wherein all or part of the non-reducing ends of N-glycoside binding sugar chains are mannose residues. The method is a method for producing glycoproteins using transformant mammalian cells which are prepared by introducing thereinto a ²-N-acetylglucosaminidase gene and inducing its expression.