| 发明名称 |
Recombinant interferon alpha 2 (IFN alpha 2) mutants |
| 摘要 |
<p>The present invention provides IFN±2 mutants and active fragments, analogs, derivatives, and variants thereof that have improved specific agonist or antagonist activity as compared to wild-type IFN±2. The present invention further provides pharmaceutical compositions comprising IFN±2 mutants useful for treating or preventing cancer, autoimmune diseases, infectious diseases or disorders associated with increased expression of IFN±2.</p> |
| 申请公布号 |
EP2476428(B1) |
申请公布日期 |
2013.08.21 |
| 申请号 |
EP20120154308 |
申请日期 |
2006.06.28 |
| 申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
SCHREIBER, GIDEON;ROISMAN, LAILA C.;JAITIN, DIEGO;KALIE, EYAL |
| 分类号 |
A61K38/21 |
主分类号 |
A61K38/21 |
| 代理机构 |
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