发明名称 |
SKIN EXTERNAL COMPOSITION FOR INHIBITING EPIDERMAL HYPERPROLIFERATION AND ALLEVIATING INFLAMMATORY SKIN DISEASES CONTAINING ORTHO-DIHYDROXYISOFLAVONE DERIVATIVES |
摘要 |
Disclosed herein is a skin external composition for inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases, which contains ortho-dihydroxyisoflavone derivatives as an active ingredient. Specifically, the skin external external composition contains the ortho-dihydroxyisoflavone derivatives, 4′,6,7-trihydroxyisoflavone, 3′,4′,7-trihydroxyisoflavone or a mixture thereof, and thus increases the expression of DKK3 protein and FZD1 protein, which appropriately control Wnt signaling, thereby inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases caused by epidermal hyperproliferation. |
申请公布号 |
EP2349254(A4) |
申请公布日期 |
2013.08.21 |
申请号 |
EP20090827701 |
申请日期 |
2009.11.17 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
PARK, JUN SEONG;PARK, HYE YOON;KIM, DONG HYUN;LEE, SANG MIN;SHIN, DONG WOOK;KIM, SHIN HYOUNG;NOH, MIN SOO;KIM, DUCK HEE;KIM, HAN KON |
分类号 |
A61K31/366;A61K9/00;A61K31/352;A61P17/00 |
主分类号 |
A61K31/366 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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