发明名称 |
A CORYNEBACTERIA STRAIN FOR ENHANCEMENT OF 5'-GUANOSINE MONOPHOSPHATE PRODUCTIVITY AND A METHOD OF PRODUCING 5'-GUANOSINE MONOPHOSPHATE USING THE SAME |
摘要 |
Disclosed is a method of producing 5'-guanosine monophosphate using a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type, thereby showing improved ATP productivity. Also, a novel microorganism is disclosed. The method comprises: culturing the corynebacteria strain which is enhanced in malate dehydrogenase activity over the endogenous activity, thus producing ATP in high yield; producing XMP in the culture; adding to the culture an enzyme or microorganism having XMP amination activity; and obtaining GMP from the culture. |
申请公布号 |
EP2358865(A4) |
申请公布日期 |
2013.08.21 |
申请号 |
EP20090833644 |
申请日期 |
2009.12.17 |
申请人 |
CJ CHEILJEDANG CORPORATION |
发明人 |
CHO, JINMAN;KIM, HYE WON;OH, YOON SEOK;PARK, JANG HEE |
分类号 |
C12N1/20;C12N9/04;C12P19/02;C12P19/32 |
主分类号 |
C12N1/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|