发明名称 |
Novel nucleic acid base pair |
摘要 |
<p>A novel artificial nucleic acid base pair which is obtained by forming a selective base pair by introducing a group having steric hindrance (preferably a group having steric hindrance and static repulsion and a stacking effect) and can be recognized by a polymerase such as DNA polymerase; a novel artificial gene; and a method of designing nucleic acid bases so as to form a selective base pair with the use of steric hindrance, static repulsion and stacking effect at the base moiety of the nucleic acid. An artificial nucleic acid comprising these bases; a process for producing the same; a codon containing the same; a nucleic acid molecule containing the same; a process for producing a non-natural gene by using the same; a process for producing a novel protein by using the above nucleic acid molecule or non-natural gene, and the like.</p> |
申请公布号 |
EP2221311(B1) |
申请公布日期 |
2013.08.21 |
申请号 |
EP20100003749 |
申请日期 |
2000.07.14 |
申请人 |
TAGCYX BIOTECHNOLOGIES |
发明人 |
HIRAO, ICHIRO;ISHIKAWA, MASAHIDE;FUJIHARA, TSUYOSHI;YOKOYAMA, SHIGEYUKI |
分类号 |
C07H11/04;C07H19/207;C07H21/00;C12N1/21;C12N15/11;C12P21/02 |
主分类号 |
C07H11/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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