发明名称 |
FACTOR IXA FOR THE TREATMENT OF BLEEDING DISORDERS |
摘要 |
The invention provides a method of treating bleeding disorders in a subject by administration of a preparation enriched for Factor IXa. The Factor IXa can be produced by proteolytically activating recombinantly-produced Factor IX. The invention also provides an improved method for producing Factor IXa from a plasma fraction, which method results in a Factor IXa product containing little or no prekallikrein activity, thus reducing the incidence of undesired side effects in a subject.
|
申请公布号 |
CA2557061(C) |
申请公布日期 |
2013.08.20 |
申请号 |
CA20052557061 |
申请日期 |
2005.02.28 |
申请人 |
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A. |
发明人 |
DONOVAN, SHANE;BAKER, DONALD A. |
分类号 |
A61K38/36;A61K38/48;A61P7/04 |
主分类号 |
A61K38/36 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|