发明名称 COMBINATION THERAPY COMPRISING VEMURAFENIB AND AN INTERFERON FOR USE IN THE TREATMENT OF CANCER
摘要 The present invention relates to a combination therapy of propane-1-sulfonic acid{3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl-2,4-difluoro-phenyl]-amide}, or a pharmaceutically acceptable salt thereof, and an interferon for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the interferon is peginterferon alfa-2a and the disorder is melanoma containing the V600E b-Raf mutation.
申请公布号 KR20130092617(A) 申请公布日期 2013.08.20
申请号 KR20137017902 申请日期 2011.12.12
申请人 F. HOFFMANN-LA ROCHE AG 发明人 DHINGRA KAPIL;HIGGINS BRIAN;KOLINSKY KENNETH;LEE RICHARD J.;LESTINI BRIAN;PACKMAN KATHRYN E.;SU FEI
分类号 A61K31/437;A61K38/21;A61P35/00 主分类号 A61K31/437
代理机构 代理人
主权项
地址