发明名称 |
Compositions and methods for the treatment of cancer |
摘要 |
The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIIb) Where U is independently selected from: (I) or (II) where U is independently selected from:
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申请公布号 |
US8513292(B2) |
申请公布日期 |
2013.08.20 |
申请号 |
US20080664345 |
申请日期 |
2008.06.19 |
申请人 |
WESTLUND NEIL;HILL JASON;ASHWELL MARK A.;NAMDEV NIVEDITA;WANG JIANQIANG;ALI SYED;ARQULE, INC. |
发明人 |
WESTLUND NEIL;HILL JASON;ASHWELL MARK A.;NAMDEV NIVEDITA;WANG JIANQIANG;ALI SYED |
分类号 |
A61K31/437;C07D221/06;C07D471/06 |
主分类号 |
A61K31/437 |
代理机构 |
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地址 |
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