发明名称 Neprilysin inhibitors
摘要 In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, R4, and R5 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 US8513244(B2) 申请公布日期 2013.08.20
申请号 US201213474987 申请日期 2012.05.18
申请人 GENDRON ROLAND;HUGHES ADAM D.;THERAVANCE, INC. 发明人 GENDRON ROLAND;HUGHES ADAM D.
分类号 A61K31/5355;A61K31/4155;A61K31/422;A61K31/4427;A61K31/4523;A61K31/497;A61K31/506;C07D231/10;C07D239/02;C07D261/06;C07D401/02;C07D413/02 主分类号 A61K31/5355
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