发明名称 |
Compounds and methods of use thereof for assaying lysophospholipase D activity |
摘要 |
Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD activity levels in normal events such as pregnancy or disease states such as cancer. In addition, the present invention can be adopted to high throughout screening (HTS) for identification of potential inhibitors of lysoPLD activity.
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申请公布号 |
US8512971(B2) |
申请公布日期 |
2013.08.20 |
申请号 |
US20100800339 |
申请日期 |
2010.05.12 |
申请人 |
FERGUSON COLIN;PRESTWICH GLENN;MADAN DAMIAN;ECHELON BIOSCIENCES, INC. |
发明人 |
FERGUSON COLIN;PRESTWICH GLENN;MADAN DAMIAN |
分类号 |
C12Q1/44;C12Q1/34 |
主分类号 |
C12Q1/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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