Low-permeability, laser-activated drug delivery device
摘要
An implantable drug delivery device that uses multiple reservoir elements to contain and release doses of active pharmaceutical ingredients. The device includes a first shell element, which has a first enclosed cavity volume and forms a low-permeability barrier. The first shell element is configured to absorb light irradiation from a laser source, the laser irradiation causing a breach in the first shell element. A first active pharmaceutical ingredient is contained in the first enclosed cavity volume and is released when the first shell element is breached. The device also includes a second shell element, which has a second enclosed cavity volume and also forms a low- permeability barrier. A second active pharmaceutical ingredient is contained in the second enclosed cavity volume. The device also includes an envelope element containing the first and second shell elements.
申请公布号
AU2011213616(B2)
申请公布日期
2013.08.15
申请号
AU20110213616
申请日期
2011.02.08
申请人
ON DEMAND THERAPEUTICS, INC.;MICROCHIPS, INC.
发明人
COPPETA, JONATHAN ROBERT;HORNE, KENNETH N.;SANTINI, JOHN T.;SCHOLL, JOHN A.;SPOONER, GREGORY J.R.;STEVENSON, CYNTHIA L.;SHAMS, NAVEED;POUTIATINE, ANDREW