发明名称 MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA
摘要 Methods are provided for detecting the amount of one or more CAH panel analytes (i.e., pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA), androstenedione, testosterone, deoxycorticosterone, 11-deoxycortisol, and cortisol) in a sample by mass spectrometry. The methods generally involve ionizing one or more CAH panel analytes in a sample and quantifying the generated ions to determine the amount of one or more CAH panel analytes in the sample. In methods where amounts of multiple CAH panel analytes are detected, the amounts of multiple analytes are detected in the same sample injection.
申请公布号 US2013206981(A1) 申请公布日期 2013.08.15
申请号 US201313851621 申请日期 2013.03.27
申请人 QUEST DIAGNOSTICS INVESTMENTS INCORPORATED;QUEST DIAGNOSTICS INVESTMENT INCORPORATED 发明人 GHOSHAL AMIT;CLARKE NIGEL J.;GOLDMAN MILDRED M.
分类号 G01N33/74;H01J49/00 主分类号 G01N33/74
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