发明名称 DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN
摘要 Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
申请公布号 WO2013120060(A1) 申请公布日期 2013.08.15
申请号 WO2013US25541 申请日期 2013.02.11
申请人 THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS;KITASATO UNIVERSITY;MONTEFIORE MEDICAL CENTER 发明人 PONNAPAKKAM, TULASI;PHILOMINATHAN, SAGAYA, THERESA LEENA;SAKON, JOSHUA;KATIKANENI, RANJITHA;KOIDE, TAKAKI;MATSUSHITA, OSAMU;GENSURE, ROBERT, C.
分类号 A61K38/46;A61K38/29;C07K1/00;C12N9/14 主分类号 A61K38/46
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