DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN
摘要
Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
申请公布号
WO2013120060(A1)
申请公布日期
2013.08.15
申请号
WO2013US25541
申请日期
2013.02.11
申请人
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS;KITASATO UNIVERSITY;MONTEFIORE MEDICAL CENTER