发明名称 |
FUSION PROTEIN CONTAINING VEGI, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF |
摘要 |
Provided is an anti-angiogenic fusion protein, which comprises a vascular endothelial cell growth inhibitor (VEGI) or variant thereof, and other polypeptide such as IgG Fc. The fusion protein optionally comprises a linker. The fusion protein can induce the apoptosis of endothelial cells and inhibit the growtth of endothelial cells, so as to be used for treating tumor. Also provided are a pharmaceutical composition and use of the fusion protein.
|
申请公布号 |
US2013211051(A1) |
申请公布日期 |
2013.08.15 |
申请号 |
US201013878495 |
申请日期 |
2010.12.27 |
申请人 |
SUN XIANGMING;ZHOU LING;HONG JIANNAN;WU YUN;BAO JUN;SHANGHAI KEXIN BIOTECH CO., LTD. |
发明人 |
SUN XIANGMING;ZHOU LING;HONG JIANNAN;WU YUN;BAO JUN |
分类号 |
C07K14/435;C07K16/18 |
主分类号 |
C07K14/435 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|