发明名称 |
SYNTHESIS OF WATER-SOLUBLE PHOSPHINE OXIDES BY PD/C-CATALYZED P-C COUPLING IN WATER |
摘要 |
<p>Cross-coupling between diphenylphosphine oxide and halogenated benzoic acids catalyzed by Pd/C in water is a green, simple and fast protocol to obtain water-soluble tertiary phosphine oxides without the addition of ligands and additives. Low reaction times, microwave irradiation, and high substrate scope make this method general and excellent for lab- and large-scale synthesis without the need to use organic solvents for neither reaction nor workup.</p> |
申请公布号 |
WO2013117440(A1) |
申请公布日期 |
2013.08.15 |
申请号 |
WO2013EP51405 |
申请日期 |
2013.01.25 |
申请人 |
PAUL SCHERRER INSTITUT |
发明人 |
RANOCCHIARI, MARCO;RUMMELT, STEPHAN;VAN BOKHOVEN, JEROEN A. |
分类号 |
C07F9/53 |
主分类号 |
C07F9/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|