Substituted carbinol compound having cyclic linker

摘要

Disclosed is a novel LXRβagonist which is useful as a prophylactic and/or therapeutic agent for arteriosclerosis such as atherosclerosis and arteriosclerosis associated with diabetes, dyslipidemia, hypercholesterolemia, lipid-related diseases, inflammatory diseases induced by inflammatory cytokines, skin diseases such as allergic skin diseases, diabetes or Alzheimer’s disease.  The LXRβagonist is a carbinol compound represented by general formula (I), a salt of the carbinol compound, or a solvate of the carbinol compound or the salt.