发明名称 |
Foamy viral envelope genes |
摘要 |
<p>Summary The present invention concerns the technical field of nucleic acids and expression-optimized nucleic acids. The present invention concerns especially nucleic acids comprising a mutated foamy viral envelope gene encoding a foamy viral envelope polypeptide, which comprises a leader peptide (LP), a surface unit (SU) and a transmembrane domain (TM). The present invention also relates to modified polypeptides encoded by these nucleic acids. Furthermore, the present invention regards a method for preparing pseudotyped vector particles as well as a method for treating a genetic disorder comprising administering a nucleic acid or a polypeptide encoded by that nucleic acid.</p> |
申请公布号 |
EP2138584(B1) |
申请公布日期 |
2013.08.14 |
申请号 |
EP20080011698 |
申请日期 |
2008.06.27 |
申请人 |
VECTORIA FORSCHUNGSFOERDERUNGS VEREIN E.V. |
发明人 |
LINDEMANN, DIRK;STIRNNAGEL, KRISTIN;LUEFTENEGGER, DANIEL |
分类号 |
C12N15/867;A61K48/00 |
主分类号 |
C12N15/867 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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