发明名称 |
COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS |
摘要 |
<p>Disclosed are use of a benzophenone derivative represented by general formula (I) or a salt thereof and one or more immunosuppressing agents in combination, and a pharmaceutical composition containing the benzophenone derivative or a salt thereof and one or more immunosuppressing agents. The use and the composition are useful for treatment or prevention of autoimmune diseases and the like. (In the formula, R 1 represents an optionally substituted heterocyclic group, a substituted phenyl group or the like; Z represents an alkylene group or the like; R 2 represents a carboxyl group, which may be protected by an alkyl group, or the like; R 3 represents an optionally protected hydroxyl group or the like; R 4 represents an optionally substituted cycloalkyloxy group or the like; and R 5 represents a hydrogen atom or the like.)</p> |
申请公布号 |
EP2266557(B1) |
申请公布日期 |
2013.08.14 |
申请号 |
EP20090735250 |
申请日期 |
2009.04.20 |
申请人 |
TOYAMA CHEMICAL CO., LTD. |
发明人 |
AIKAWA, YUKIHIKO;SHIOZAWA, SHUNICHI |
分类号 |
A61K31/194;A61K31/42;A61K31/423;A61K31/519;A61K31/5377;A61K31/573;A61K45/06;A61P29/00;A61P37/06;A61P43/00 |
主分类号 |
A61K31/194 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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