发明名称 |
MODULATORS FOR AMYLOID BETA |
摘要 |
<p>The invention relates to compounds of formula wherein the substituents are as described in claim 1. Compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of beta-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.</p> |
申请公布号 |
EP2257541(B1) |
申请公布日期 |
2013.08.14 |
申请号 |
EP20090713519 |
申请日期 |
2009.02.12 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BAUMANN, KARLHEINZ;FLOHR, ALEXANDER;GOETSCHI, ERWIN;JACOBSEN, HELMUT;JOLIDON, SYNESE;LUEBBERS, THOMAS |
分类号 |
C07D401/12;A61K31/4196;A61K31/4439;A61K31/506;A61P25/28;C07D401/14;C07D403/12;C07D403/14;C07D409/14;C07D413/12;C07D413/14;C07D417/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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