| 摘要 |
This application describes methods and apparatus for chemical sensing using surface wave resonance, such as surface plasmon resonance (SPR). A sensor is described having at least one layer (102, 103) of a metallic or lossy dielectric material configured to support surface waves. At least two sensing layers (104, 105, 106, 107) are provided, each adjacent a different surface of a metallic/lossy dielectric layer, with the lossy dielectric and sensing layers arranged in a multilayer stack in a direction substantially perpendicular to the layers. Advantageously there are at least two dielectric/lossy dielectric layers (102, 103) and at least some of the sensing layers are sensitive to different target chemicals. By analysing any detected change in resonance the relevant interface leading to such change can be identified and hence multi-analyte sensing capability is provided in the multi-layer sensor. |
