发明名称 TRIAZOLE DERIVATIVE OR SALT THEREOF
摘要 A triazole compound represented by the formula (I) or a salt thereof: (see formula I) wherein R1: -N(C1-6 alkyl)2 or -X-R4; R4: optionally substituted phenyl; X: -O-, -N(R0)-, -N(R0)S(O)2- or -N(R0)C(O)-; R0: the same or different from each other, -H or C1-6 alkyl; R2: -C1-6 alkyl or cycloalkyl; R3: optionally substituted phenyl; A and B: the same or different from each other, C1-6 alkyl. The triazole compound has a potent 11.beta.-HSD1 inhibitory activity, exhibits an excellent hypoglycerin effect which makes it usable in treating diabetes and insulin resistance.
申请公布号 CA2580409(C) 申请公布日期 2013.08.13
申请号 CA20052580409 申请日期 2005.09.14
申请人 ASTELLAS PHARMA INC. 发明人 MURAKAMI, TAKESHI;KAWANO, TOMOAKI;SHIRAKI, RYOTA;ISHII, HIROFUMI;YOSHIMURA, SEIJI;OHKAWA, TAKEHIKO;HOSAKA, MITSURU;FUKUDOME, HIROKI;INOKI, YUTAKA
分类号 C07D249/08;A61K31/4196;A61K31/4439;A61K31/454;A61K31/55;A61P3/04;A61P3/06;A61P3/10;A61P9/12;A61P19/10;A61P25/28;A61P27/06;A61P43/00;C07D401/08;C07D403/08;C07D409/08;C07D487/04 主分类号 C07D249/08
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