发明名称 |
Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics |
摘要 |
A patient suffering from an endobronchial infection is treated by administering to the patient for inhalation a dose of less than about 4.0 ml of a nebulized aerosol formulation comprising from about 60 to about 200 mg/ml of an aminoglycoside antibiotic, such as tobramycin, in a physiologically acceptable carrier in a time period of less than about 10 minutes. Unit dose devices for storage and delivery of the aminoglycoside antibiotic formulations are also provided.
|
申请公布号 |
US8507454(B2) |
申请公布日期 |
2013.08.13 |
申请号 |
US201113295228 |
申请日期 |
2011.11.14 |
申请人 |
SPEIRS ROBERT J;SCHAEFFLER BARBARA A;CHALLONER PETER B;NOVARTIS AG |
发明人 |
SPEIRS ROBERT J;SCHAEFFLER BARBARA A;CHALLONER PETER B |
分类号 |
A61K9/72;A61K31/70;A61K9/00;A61K9/12;A61K31/7036;A61K51/04;A61P11/00;A61P31/04 |
主分类号 |
A61K9/72 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|