发明名称 |
Methods of use for an antibody against human frizzled receptors 1, 2, 5, 7 or 8 |
摘要 |
Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.
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申请公布号 |
US8507442(B2) |
申请公布日期 |
2013.08.13 |
申请号 |
US201113164191 |
申请日期 |
2011.06.20 |
申请人 |
GURNEY AUSTIN L.;SATO AARON KEN;AXELROD FUMIKO TAKADA;HOEY TIMOTHY CHARLES;SATYAL SANJEEV H.;MITRA SATYAJIT SUJIT KUMAR;ONCOMED PHARMACEUTICALS, INC. |
发明人 |
GURNEY AUSTIN L.;SATO AARON KEN;AXELROD FUMIKO TAKADA;HOEY TIMOTHY CHARLES;SATYAL SANJEEV H.;MITRA SATYAJIT SUJIT KUMAR |
分类号 |
A61K38/00;A61K39/395;C07K16/00;C12P21/08 |
主分类号 |
A61K38/00 |
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地址 |
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