摘要 |
FIELD: biotechnologies.SUBSTANCE: invention is related to a compound of a formula, where R' is the below formula, and R" is hydrogen, in free form or in the form of a pharmaceutically acceptable acid-additive salt. Proposed compounds of the formula (IA) inhibit activity of DPP-IV (dipeptidylpeptidase-IV).EFFECT: compounds are justified for application as medicinal agents designed for inhibition of DPP-IV and for treatment of conditions mediated by DPP-IV, such as achrestic diabetes.11 cl, 2 ex, 2 dwg, 7 tbl |