发明名称 |
PERFUSION ASSESSMENT USING TRANSMISSION LASER SPECKLE IMAGING |
摘要 |
Methods and apparatus for measuring perfusion using transmission laser speckle imaging are provided. The apparatus comprises a coherent light source and a detector configured to measure transmitted light associated with an unfocused image at one or more locations. The coherent light source and detector are positioned in a transmission geometry. The apparatus further comprises means for securing the coherent light source and the detector to the tissue sample in a fixed transmission geometry relative to the tissue sample. The apparatus may further comprise at least one processor to receive information from the detector and process detected variations in transmitted light intensity to determine a single metric of perfusion. The method may comprise the steps transilluminating a tissue sample with coherent light, recording spatial and/or temporal variations in the transmitted light signal, determining speckle contrast value(s), and computing a metric of perfusion.
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申请公布号 |
US2013204112(A1) |
申请公布日期 |
2013.08.08 |
申请号 |
US201313762316 |
申请日期 |
2013.02.07 |
申请人 |
WHITE SEAN MICHAEL;YANG BRUCE YEE;RICE TYLER BYWATERS;LASER ASSOCIATED SCIENCES, LLC |
发明人 |
WHITE SEAN MICHAEL;YANG BRUCE YEE;RICE TYLER BYWATERS |
分类号 |
A61B5/026 |
主分类号 |
A61B5/026 |
代理机构 |
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