发明名称 |
ANTIBODIES DIRECTED AGAINST IL-17 |
摘要 |
The disclosure relates to an isolated IL-17-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1 and optionally an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The disclosure also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease. |
申请公布号 |
US2013202591(A1) |
申请公布日期 |
2013.08.08 |
申请号 |
US201113814262 |
申请日期 |
2011.08.02 |
申请人 |
HORLICK ROBERT;KING DAVID;BOWERS PETER;DALTON JENNIFER;WU BETTY;ROBERTS TRACI;ZHANG XUE;ALTOBELL, III LAURENCE;ANAPTYSBIO, INC. |
发明人 |
HORLICK ROBERT;KING DAVID;BOWERS PETER;DALTON JENNIFER;WU BETTY;ROBERTS TRACI;ZHANG XUE;ALTOBELL, III LAURENCE |
分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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