发明名称 |
HYPERSULFATED DISACCHARIDES TO TREAT ELASTASE RELATED DISORDERS |
摘要 |
Hypersulfated disaccharides of formula I and other hypersulfated disaccharides disclosed herein are used to treat diseases or conditions associated with human neutrophil elastase imbalances. The disaccharides and/or intermediates useful to prepare such compounds are prepared from heparin. The diseases and conditions which are treated with a compound of formula I include chronic obstructive pulmonary disorder (COPD) and cystic fibrosis (CF). The formulations are delivered to the lungs in an aerosol formulation or dry powder means or via nebulization. Oral forms are also suitable.
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申请公布号 |
US2013203695(A1) |
申请公布日期 |
2013.08.08 |
申请号 |
US201113880875 |
申请日期 |
2011.10.27 |
申请人 |
AHMED TAHIR;ABRAHAM WILLIAM;OPKO HEALTH, INC. |
发明人 |
AHMED TAHIR;ABRAHAM WILLIAM |
分类号 |
C13K13/00;A61K31/7016;A61K45/06 |
主分类号 |
C13K13/00 |
代理机构 |
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