| 发明名称 |
PROCESS OF OBTAINING GLYCOPROTEIN COMPOSITION WITH INCREASED AFUCOSYLATION CONTENT |
| 摘要 |
<p>The invention describes a cell culture process for obtaining a glycoprotein with the enhanced afucosylation content. The method involves culturing cells in a medium supplemented with galactose, at a specific osmolality, and harvesting on about 12th day or at about 50% viability to obtain glycoform composition with enhanced afucosylation.</p> |
| 申请公布号 |
WO2013114165(A1) |
申请公布日期 |
2013.08.08 |
| 申请号 |
WO2012IB57091 |
申请日期 |
2012.12.08 |
| 申请人 |
DR REDDY'S LABORATORIES LIMITED |
发明人 |
MAKKAPATI, SATAKARNI;NIKAM, VAIBHAV S;SUBRAHMANYAM, SATYAM |
| 分类号 |
C07K14/435;C12N5/00 |
主分类号 |
C07K14/435 |
| 代理机构 |
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