Provided herein is technology related to the chemical modification and purification of DNA. Specifically, the technology provides methods for performing a bisulfite conversion reaction on small amounts of single-stranded, fragmented DNA and performing the subsequent desulfonation and purification steps on magnetic beads.
申请公布号
CA2863215(A1)
申请公布日期
2013.08.08
申请号
CA20132863215
申请日期
2013.01.30
申请人
EXACT SCIENCES CORPORATION
发明人
DOMANICO, MICHAEL J.;ALLAWI, HATIM;LIDGARD, GRAHAM P.;AIZENSTEIN, BRIAN;HUNT, OLIVER;ZUTZ, TOBIAS CHARLES
