| 摘要 |
<p>The present invention relates to a composition for aggregating a biological sample which is used for preparing a paraffin block for observing a biological sample, to a method for preparing a paraffin block using same, and to a method for microscopic observation of a biological sample using the paraffin block, and more particularly, to a composition for aggregating a biological sample comprising a first composition and a second composition, to a method for preparing a paraffin block using the composition, and to a method for microscopic observation of a biological sample using the prepared paraffin block, wherein the first composition comprises one or more water-soluble polymer(s) selected from the group consisting of polyvinyl alcohol, polyethylene oxide, polyacrylamide, polyvinyl pyrrolidone, polyacrylic acid, polyethyleneimine, polyamine, polyamideamine, and polydiallyldimethylammonium chloride, and distilled water, and the second composition comprises: one or more organic solvent(s) selected from the group consisting of alcohol, xylene, and acetone; and one or more medical adhesive(s) selected from the group consisting of cyanoacrylate, a fibrin glue, a protein glue, and a sealant containing polyurethane and polyethylene glycol (PEG). According to the present invention, in the case in which the paraffin block is prepared using tissue or cells which are traces of fluidic biological samples, since a process of preparing a biological sample composite is performed in the centrifuge tube using a centrifuge, the present invention can minimize the loss and dissipation of the biological sample, reduce background staining, perform a process of preparing a paraffin block in an easy manner, save time and the cost for preparing the paraffin block, and improve the quality of a slide sectioned from the paraffin block.</p> |
