| 摘要 |
The invention relates to the use of one of more biomarkers, such as granzyme B, to determine an immune response, such as a cell-mediated immune response, of a subject to an immunostimulatory composition. The invention also relates to methods of treating a subject determined to develop a poor immune response to an immunostimulatory composition. Further, the invention relates to kits for use in practicing methods of the invention. |
| 申请人 |
ADVANCED MEDICAL RESEARCH INSTITUTE OF CANADA;UNIVERSITY OF CONNECTICUT;THE KINGDOM OF THE NETHERLANDS, REPRESENTED BY THE MINISTER OF PUBLIC HEALTH, WELFARE AND SPORTS, ON BEHALF OF THE MINISTER, THE NETHERLANDS VACCINE INSTITUTE;EBERHARD KARLS UNIVERSITAT TUBINGEN |
发明人 |
ZHOU, XIN;SOETHOUT, ERNST CHRISTIAAN;PAWELEC, GRAHAM;MCELHANEY, JANET |
