发明名称 CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS
摘要 There are provided bicyclic carbonylamino-pyrazoles of formula (I), wherein the variables are as specified in the claims, for use as medicament, in particular for the treatment of diseases due to the malfunctioning of protein kinases (PKs), such as cancer, pharmaceutical compositions comprising such carbamoyl derivatives, and their use as prodrugs of therapeutically active agents. Method of treatment and some new bicyclic carbonylamino-pyrazoles are also object of the present invention.
申请公布号 US2013203770(A1) 申请公布日期 2013.08.08
申请号 US201213630009 申请日期 2012.09.28
申请人 NERVIANO MEDICAL SCIENCES S.R.L.;NERVIANO MEDICAL SCIENCES S.R.L. 发明人 PULICI MAURIZIO;POLUCCI PAOLO
分类号 A61K31/496;A61K31/4162;A61K31/454 主分类号 A61K31/496
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