发明名称 NOVEL CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING SAME, ANTI-INFECTIVE AGENT, ANTIBIOTIC-CONTAINING FRACTION, ANTIBIOTIC, METHOD FOR PRODUCING ANTIBIOTIC, ANTIBIOTIC-PRODUCING MICROORGANISM, AND ANTIBIOTIC PRODUCED BY SAME
摘要 Provided are: a novel compound having a structure different from that of existing drugs; a novel microorganism capable of producing the novel compound; and further; a novel compound effective to a multiple-drug-resistant bacterium. To provide a novel compound having a high therapeutic effect which can be expected to have a low hurdle for practical realization by selecting an intended compound from many candidate compounds based not only on an antibacterial activity but also on evaluation including a therapeutic effect, a cyclic peptide compound shown by the following formula (1) or a pharmaceutically allowable salt thereof and a microorganism with Accession No. NITE BP-870 or a microorganism mutated naturally or artificially therefrom are provided. (In the formula (1), R1 represents an acyl group having 7, 8, or 9 carbon atoms and optionally containing a substituent group; R2 represents a methyl group or a hydrogen atom; and R3 represents an ethyl group or a methyl group.)
申请公布号 US2013203654(A1) 申请公布日期 2013.08.08
申请号 US201113699161 申请日期 2011.05.25
申请人 SEKIMIZU KAZUHISA;HAMAMOTO HIROSHI;MURAKAMI KAZUHISA;THE UNIVERSITY OF TOKYO;GENOME PHARMACEUTICALS INSTITUTE CO., LTD. 发明人 SEKIMIZU KAZUHISA;HAMAMOTO HIROSHI;MURAKAMI KAZUHISA
分类号 C07K7/56;C12N1/20;C12R1/01 主分类号 C07K7/56
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