发明名称 |
METHOD FOR THE DETECTION OF A BINDING PARTNER OF A MULTISPECIFIC BINDER |
摘要 |
Herein is reported a method for the detection of free antigen of a multispecific antibody in a sample, whereby the antigen to be detected can be specifically bound by a first binding site of the multispecific antibody, comprising the step of incubating a sample comprising free antigen and multispecific antibody with an anti-idiotypic antibody, which specifically binds to a second binding specificity of the bispecific antibody, which is different from the first binding specificity, whereby the anti-idiotypic antibody is bound to a solid phase. |
申请公布号 |
WO2013113663(A1) |
申请公布日期 |
2013.08.08 |
申请号 |
WO2013EP51604 |
申请日期 |
2013.01.29 |
申请人 |
F. HOFFMANN-LA ROCHE AG;STUBENRAUCH, KAY-GUNNAR;WESSELS, UWE |
发明人 |
STUBENRAUCH, KAY-GUNNAR;WESSELS, UWE |
分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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