| 摘要 |
According to the invention there is provided a non-invasive method for the diagnosis of adenocarcinoma or their precursor lesions in a female subject by analyzing cells of said subject, comprising - preparing epithelial cells of a sample of said subject obtained from a rinse of the uterine cavity and optionally the fallopian tubes, and - performing analysis in said cells to determine an abnormality associated with ovarian or endometrial cancer, the abnormality being indicative of adenocarcinoma or their precursor lesions. The invention further provides a kit for diagnosing adenocarcinoma in a female subject on the basis of an abnormality in a cell sample of said subject, comprising - an uterine catheter designed for non-invasive rinsing of the uterine cavity and collecting a sample of the rinse, - means to prepare a fraction of epithelial cells of said sample, and - reagents for analyzing said cells to determine an abnormality associated with ovarian or endometrial cancer, and the use of such kit e.g. for a screening test. |
