The present invention relates to a method of preparing an insoluble separation matrix, which method comprises salt-treatment of a polysaccharide gel followed by cross-linking of the polysaccharide polymers. In one embodiment, the method comprises providing an aqueous solution of a gelatable native polysaccharide; lowering the temperature of the polysaccharide solution to a value below its gelling point; salt-treatment by adding at least one salt to the resulting polysaccharide; and cross-linking the salt-treated polysaccharide. The polysaccharide may be prepared e.g. into particles, membranes or monoliths.
申请公布号
EP1904226(A4)
申请公布日期
2013.08.07
申请号
EP20060747969
申请日期
2006.06.28
申请人
GE HEALTHCARE BIO-SCIENCES AB
发明人
BERG, HANS;HOLM, MARIA;BUCKLEY, DAVID;BUSSON, PHILIPPE;HAGVALL, ANDERS;HOLMGREN, EVA;IHRE, HENRIK;LARSSON, ANDERS;LINDSTROEM, DAG