发明名称 CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL FOR TREATING AUTOIMMUNE DISEASES
摘要 <p>The present invention relates to a compound of Antrodia camphorata used to treat autoimmune diseases, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, isolated from Antrodia camphorata, and its use in alleviating symptoms of autoimmune diseases such as systemic lupus erythematosus (SLE). The cyclohexenone compound according to the present invention helps to decrease proteinuria levels and antinuclear antibody titers in SLE mammals in order to alleviate kidney inflammation and disease, as well as the self-damage caused by antinuclear antibodies. The purpose for prevention and treatment of autoimmune diseases and kidney diseases by the natural, side-effect free substance can then be accomplished.</p>
申请公布号 EP2221291(B1) 申请公布日期 2013.08.07
申请号 EP20080714807 申请日期 2008.01.31
申请人 GOLDEN BIOTECHNOLOGY CORPORATION 发明人 LIU, SHENG-YUNG;WEN, WU-CHE;KUO, MAO-TIEN
分类号 C07C49/743;A61K31/12;A61K31/122;A61P37/00;A61P37/06;C07C45/78;C07C49/587;C07C49/703;C07C403/02 主分类号 C07C49/743
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