发明名称 |
AN OLIGONUCLEOTIDE OR ITS FUNCTIONAL HOMOLOGUE, A COMPOSITION COMPRISING THE SAME AND A METHOD FOR TREATING B CELL NEOPLASM |
摘要 |
The invention provides nine oligonucleotides with sequences of SEQ ID NO: 1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonucleotides or their functional homologues or the composition comprising the oligonucleotides. The oligonucleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B cell neoplastic cells. |
申请公布号 |
KR101294131(B1) |
申请公布日期 |
2013.08.07 |
申请号 |
KR20077028308 |
申请日期 |
2006.02.13 |
申请人 |
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发明人 |
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分类号 |
C07H21/04;C12N15/117;C12N15/63 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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