发明名称 |
TARGETED GLYCOSAMINOGLYCAN POLYMERS BY POLYMER GRAFTING AND METHODS OF MAKING AND USING SAME |
摘要 |
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size. The present invention also relates to methodology for polymer grafting by a polysachharide synthase to form glycosaminoglycan polymers having an unnatural structure. |
申请公布号 |
EP2079846(A4) |
申请公布日期 |
2013.08.07 |
申请号 |
EP20070874512 |
申请日期 |
2007.10.03 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA |
发明人 |
DEANGELIS, PAUL, L.;SISMEY-RAGATZ, ALISON |
分类号 |
C12P19/18;C08B37/00;C08B37/08;C12P19/28 |
主分类号 |
C12P19/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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