发明名称 |
Optically active compound of prulifloxacin for treating infection and preparation method thereof |
摘要 |
Anti-infection levorotatory optically active compound (S-configuration) of prulifloxacin represented by the following formula (1) and preparation method thereof are disclosed. Said method utilizes levorotatory ulifloxacin as the raw material and the reaction is conducted in organic solvent in the presence of alkaline materials, wherein the reaction temperature is -20° C.~60° C. and the reaction time is 15 minutes to 24 hours.
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申请公布号 |
US8501741(B2) |
申请公布日期 |
2013.08.06 |
申请号 |
US201013522290 |
申请日期 |
2010.10.22 |
申请人 |
YING JUN;PENG FENG;WANG YUPING;AN SUIWEI;LIANG JINQIANG;LIANG BEIMEI;NI QINGCHUN;LUO CHENG;HAINAN HUALON PHARMACEUTICAL CO., LTD. |
发明人 |
YING JUN;PENG FENG;WANG YUPING;AN SUIWEI;LIANG JINQIANG;LIANG BEIMEI;NI QINGCHUN;LUO CHENG |
分类号 |
A61K31/496;C07D495/04 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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地址 |
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