发明名称 |
Method of treating fatty liver diseases and conditions in non-lipodystrophic subjects |
摘要 |
The invention generally relates to the use of leptin in the treatment of a leptin-responsive disease or condition in a non-lipodystrophic subject. More particularly, the invention is directed to the use of leptin in the treatment of a fatty liver disease in a non-lipodystrophic subject with a relative leptin deficiency. The invention includes methods for the treatment of nonalcoholic steatohepatitis (NASH), alcoholic fatty liver disease (AFLD), and nonalcoholic fatty liver disease (NAFLD) in a non-lipodystrophic subject. The invention includes the treatment of conditions ranging from ectopic lipid accumulation (steatosis) to cirrhosis.
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申请公布号 |
US8501686(B2) |
申请公布日期 |
2013.08.06 |
申请号 |
US20090995842 |
申请日期 |
2009.06.05 |
申请人 |
ORAL ELIF A.;BURANT CHARLES F.;CHENEVERT THOMAS L.;HUSSAIN HERO K.;MCKENNA BARBARA J.;UNIVERSITY OF MICHIGAN |
发明人 |
ORAL ELIF A.;BURANT CHARLES F.;CHENEVERT THOMAS L.;HUSSAIN HERO K.;MCKENNA BARBARA J. |
分类号 |
A61K38/22;A61P3/06 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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地址 |
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