COMPOSITION CONTAINING INDOLE AND INDAZOLE DERIVATIVES FOR INHIBITION OF CANCER METASTASIS

摘要

PURPOSE: A composition containing indole and indazole derivatives as active ingredients is provided to suppress cancer metastasis and to effectively enhance a cancer therapeutic effect. CONSTITUTION: A pharmaceutical composition for suppressing cancer metastasis contains a compound of chemical formula 1 or an optical isomer thereof as an active ingredient. The compound of chemical formula 1 has an indole or indazole structure of chemical formula 2 or 3. The compound of chemical formula 1 is cyclopentyl-[2-(4,5-dihydro-1,3-thiazole-2-yl)-1H-indole-7-yl]-amine, [2-(4,5-dihydro-thiazole-2-yl)-1H-indole-7-yl]-(4-methyl-cyclohexyl)-amine, or [2-(4,5-dihydro-thiazole-2-yl)-1H-indole-7-yl]-piperidine-4-yl-amine.