发明名称 OMV VACCINES
摘要 The invention is in the field of outer membrane vesicles (OMV) and their uses. More particularly the present invention provides OMV obtained from a bacterium being an ompA mutant and/or a mutant in one or more components of the TolPal complex and presenting a heterologous antigen on its surface. The heterologous antigen is selected from the group consisting of Chlamydia trachomatis CT823, CT681, CT372, CT443, CT043, CT733, CT279, CT601 and CT153 for the treatment, prevention or diagnosis of Chlamydia infection.
申请公布号 US2013195907(A1) 申请公布日期 2013.08.01
申请号 US201113702949 申请日期 2011.06.10
申请人 GRIFANTINI RENATA MARIA;BARTOLINI ERIKA;FINCO ORETTA;GRANDI GUIDO;NORVARTIS AG 发明人 GRIFANTINI RENATA MARIA;BARTOLINI ERIKA;FINCO ORETTA;GRANDI GUIDO
分类号 A61K39/118 主分类号 A61K39/118
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